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Regionale Haeufigkeit von revaskularisierenden Prozeduren bei Karotisstenose in Deutschland

For Germany, regional variation of procedure rates of carotid endarterectomy (CEA) and carotid artery stenting (CAS) performed for carotid stenosis have so far not been analyzed at a national level. The aim of this study was to assess small area …

Bivariate spatiotemporal disease mapping of cancer of the breast and cervix uteri among Iranian women

Cervical cancer in women is one of the most common cancers and breast cancer has grown dramatically in recent years. The purpose of this study was to map the incidence of breast and cervix uteri cancer among Iranian women over a 6-year period …

Editors Choice – High Annual Hospital Volume is Associated with Decreased in Hospital Mortality and Complication Rates Following Treatment of Abdominal Aortic Aneurysms: Secondary Data Analysis of the Nationwide German DRG Statistics from 2005 to 2013

Joint Spatio-Temporal Shared Component Model with an Application in Iran Cancer Data

Spatial Analysis of Hospital Incidence and in Hospital Mortality of Abdominal Aortic Aneurysms in Germany: Secondary Data Analysis of Nationwide Hospital Episode (DRG) Data

Objective: This study aimed to analyze the spatial distribution and regional variation of the hospital incidence and in hospital mortality of abdominal aortic aneurysms (AAA) in Germany. Methods: German DRG statistics (2011–2014) were analysed. …

Fitting large-scale structured additive regression models

Fitting regression models can be challenging when regression coefficients are high-dimensional. Especially when large spatial or temporal effects need to be taken into account the limits of computational capacities of normal working stations are …

Initial high-resolution microscopic mapping of active and inactive regulatory sequences proves non-random 3D arrangements in chromatin domain clusters

Background: The association of active transcription regulatory elements (TREs) with DNAse I hypersensitivity (DHS[+]) and an open local chromatin configuration has long been known. However, the 3D topography of TREs within the nuclear landscape of …

Inzidenz, Therapie und Letalitat abdominaler Aortenaneurysmen

Maximum Entropy Approach in Dynamic Contrast-Enhanced Magnetic Resonance Imaging

Quantitative analyses of the 3D nuclear landscape recorded with super-resolved fluorescence microscopy

Recent advancements of super-resolved fluorescence microscopy have revolutionized microscopic studies of cells, including the exceedingly complex structural organization of cell nuclei in space and time. In this paper we describe and discuss tools …