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Modified Maximum Entropy Method and Estimating the AIF via DCE-MRI Data Analysis

Background: For the kinetic models used in contrast-based medical imaging, the assignment of the arterial input function named AIF is essential for the estimation of the physiological parameters of the tissue via solving an optimization problem. …

Zusammenhang zwischen der regionalen Siedlungsstruktur und der Krankenhausinzidenz, Therapieform und Mortalität von nicht-rupturierten abdominalen Aortenaneurysmen. Sekundärdatenanalyse der deutschen DRG-Statistik von 2005–2014

Co-localization analysis in fluorescence microscopy via maximum entropy copula

Co-localization analysis is a popular method for quantitative analysis in fluorescence microscopy imaging. The localization of marked proteins in the cell nucleus allows a deep insight into biological processes in the nucleus. Several metrics have …

Relationship between regional settlement structure and hospital incidence, type of therapy and mortality of non-ruptured abdominal aortic aneurysms

Introduction: In Germany, the regional settlement structure is heterogenous, ranging from densely populated cities with a tight network of vascular health care to large regions in which access to health care is limited in terms of space and time. …

Geographic risk of general and abdominal obesity and related determinants in Iranian children and adolescents: CASPIAN-IV Study

Background: Obesity, as a risk factor for many noncommunicable diseases, is a common public health problem in developed and developing countries. Among Iranian children and adolescents, the prevalence of being overweight has increased by almost 50% …

Mindestmengeneffekte bei der Therapie des abdominalen Aortenaneurysmas

Hintergrund: Die Qualitätssicherungsrichtlinie zum Bauchaortenaneurysma (abdominales Aortenaneurysma [AAA]) wurde 2008 vom Gemeinsamen Bundesausschuss (G-BA) implementiert. Ziele dieser Studie sind es, den Zusammenhang zwischen Krankenhausfallzahl …

Cohesin depleted cells pass through mitosis and reconstitute a functional nuclear architecture.

The human genome forms thousands of “contact domains”, which are intervals of enhanced contact frequency. Some, called “loop domains” are thought to form by cohesin-mediated loop extrusion. Others, called “compartmental domains”, form due to the …

Regional variation in endovascular treatment rate and in-hospital mortality of abdominal aortic aneurysms in Germany. Secondary data analysis of nationwide hospital DRG data from 2012 to 2014

Background: Abdominal aortic aneurysms (AAA) can be treated by either open surgery (OAR) or endovascular aortic repair (EVAR). The aim of this study was to analyze regional variations in application of (EVAR) and in-hospital mortality after intact …

Spatio-temporal pattern of two common cancers among Iranian woman: An adaptive smoothing model

The impact of model assumptions in scalar-on-image regression

Complex statistical models such as scalar-on-image regression often require strong assumptions to overcome the issue of non-identifiability. While in theory it is well understood that model assumptions can strongly influence the results, this seems …