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Stepwise heterogeneity analysis of breast tumors in perfusion DCE-MRI datasets

Two Tissue Compartment Model in DCE-MRI: A Bayesian Approach

In this paper, we propose a compartment model with two interstitial space compartments for the quantitative description of the contrast medium kinetics in dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI). The model accounts for …

Attenuation Resilient AIF Estimation Based on Hierarchical Bayesian Modelling for First Pass Myocardial Perfusion MRI

Non-linear attenuation of the Arterial Input Function (AIF) is a major problem in first-pass MR perfusion imaging due to the high concentration of the contrast agent in the blood pool. This paper presents a technique to reconstruct the true AIF using …

Semi-parametric analysis of dynamic contrast-enhanced MRI using Bayesian P-splines

Current approaches to quantitative analysis of DCE-MRI with non-linear models involve the convolution of an arterial input function (AIF) with the contrast agent concentration at a voxel or regional level. Full quantification provides meaningful …

COPD mortality trends 1950-1999 in England & Wales - Did the 1956 Clean Air Act make a detectable difference?